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Takashi Kawahara Selected Research

hydroxyflutamide

1/2020FOXO1 as a tumor suppressor inactivated via AR/ERĪ² signals in urothelial cells.
1/2017Enzalutamide as an androgen receptor inhibitor prevents urothelial tumorigenesis.
10/2015ELK1 is up-regulated by androgen in bladder cancer cells and promotes tumor progression.
10/2015Compound A Inhibits Bladder Cancer Growth Predominantly via Glucocorticoid Receptor Transrepression.

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Takashi Kawahara Research Topics

Disease

60Prostatic Neoplasms (Prostate Cancer)
09/2021 - 06/2005
58Neoplasms (Cancer)
01/2022 - 10/2005
36Urinary Bladder Neoplasms (Bladder Cancer)
11/2020 - 01/2014
20Carcinoma (Carcinomatosis)
09/2020 - 10/2009
17Neoplasm Metastasis (Metastasis)
03/2020 - 04/2007
15Renal Cell Carcinoma (Grawitz Tumor)
05/2019 - 04/2007
9Carcinogenesis
01/2020 - 01/2014
8Hydronephrosis
09/2020 - 01/2012
6Testicular Neoplasms (Testicular Cancer)
03/2019 - 01/2016
5Disease Progression
01/2022 - 08/2015
5Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2022 - 09/2016
5Pain (Aches)
09/2021 - 01/2012
5Non-Muscle Invasive Bladder Neoplasms
09/2020 - 01/2016
5Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2020 - 06/2013
5Calculi (Calculus)
06/2016 - 07/2012
4Pathologic Constriction (Stenosis)
01/2021 - 06/2012
4Sarcopenia
01/2021 - 01/2017
4Hypoxia (Hypoxemia)
01/2018 - 09/2007
4Kidney Calculi (Kidney Stone)
10/2012 - 01/2012
3Urinary Tract Infections (Urinary Tract Infection)
01/2021 - 12/2012
3Adenocarcinoma
08/2020 - 09/2017
3Body Weight (Weight, Body)
08/2020 - 11/2009
3Hemorrhage
03/2019 - 07/2011
3Hypogonadism (Hypergonadotropic Hypogonadism)
03/2019 - 01/2018
3Ischemia
09/2018 - 01/2013
3Penile Neoplasms (Penile Cancer)
05/2018 - 01/2016
3Sarcoma (Soft Tissue Sarcoma)
02/2016 - 10/2006
3Urinary Bladder Calculi (Bladder Calculi)
03/2013 - 08/2012
2Necrosis
08/2021 - 04/2017
2Infections
01/2021 - 01/2020
2Lower Urinary Tract Symptoms
01/2021 - 06/2013
2Ureteral Obstruction
01/2021 - 09/2020
2Stress Fractures (Stress Fracture)
08/2020 - 01/2020

Drug/Important Bio-Agent (IBA)

21AndrogensIBA
03/2021 - 04/2008
16Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2010
15Hormones (Hormone)IBA
03/2021 - 12/2005
15Androgen Receptors (Androgen Receptor)IBA
01/2021 - 01/2014
14Prostate-Specific Antigen (Semenogelase)IBA
07/2021 - 06/2005
12enzalutamideIBA
01/2021 - 10/2016
11Cisplatin (Platino)FDA LinkGeneric
05/2019 - 09/2006
10Docetaxel (Taxotere)FDA Link
01/2020 - 11/2009
8Biological ProductsIBA
12/2016 - 12/2005
7Abiraterone AcetateIBA
01/2021 - 08/2015
6GemcitabineFDA Link
09/2018 - 01/2015
5Tumor Biomarkers (Tumor Markers)IBA
11/2020 - 11/2016
5silodosinFDA Link
01/2020 - 06/2013
5bicalutamide (Casodex)FDA LinkGeneric
09/2019 - 01/2016
5Messenger RNA (mRNA)IBA
04/2019 - 01/2010
4NivolumabIBA
01/2022 - 05/2018
4Hemoglobins (Hemoglobin)IBA
09/2021 - 09/2007
4Indicators and Reagents (Reagents)IBA
01/2021 - 06/2005
4Small Interfering RNA (siRNA)IBA
01/2020 - 05/2015
4Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2014
4hydroxyflutamideIBA
01/2020 - 10/2015
4Sunitinib (Sutent)FDA Link
05/2019 - 01/2010
4Pharmaceutical PreparationsIBA
05/2019 - 06/2013
4Dexamethasone (Maxidex)FDA LinkGeneric
10/2015 - 12/2005
3Radium-223IBA
09/2021 - 01/2021
3DNA (Deoxyribonucleic Acid)IBA
01/2021 - 05/2018
3Gonadotropin-Releasing Hormone (GnRH)FDA Link
10/2020 - 01/2017
3CytokinesIBA
09/2020 - 01/2014
3Estradiol (Delestrogen)FDA LinkGeneric
08/2020 - 04/2019
3CarcinogensIBA
01/2020 - 02/2016
3Tamsulosin (Flomax)FDA LinkGeneric
01/2020 - 06/2013
3Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 11/2006
3Dihydrotestosterone (Androstanolone)IBA
01/2020 - 10/2015
3Capsules (Microcapsules)IBA
05/2019 - 09/2006
3cabazitaxelFDA Link
01/2019 - 01/2017
3ElementsIBA
09/2018 - 11/2009
3Testosterone (Sustanon)FDA Link
01/2018 - 07/2010
3Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
01/2018 - 09/2016
3Protein Isoforms (Isoforms)IBA
08/2017 - 05/2015
3Androgen Antagonists (Antiandrogens)IBA
11/2016 - 01/2016
3Flutamide (Eulexin)FDA LinkGeneric
11/2016 - 01/2016
3Proteins (Proteins, Gene)FDA Link
08/2016 - 01/2015
3Cyclosporine (Ciclosporin)FDA LinkGeneric
02/2016 - 01/2015
3Tacrolimus (Prograf)FDA LinkGeneric
02/2016 - 01/2015
3RNA (Ribonucleic Acid)IBA
01/2016 - 01/2015
3Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
10/2015 - 08/2014

Therapy/Procedure

38Therapeutics
03/2021 - 03/2004
31Castration
09/2021 - 01/2012
28Drug Therapy (Chemotherapy)
01/2022 - 03/2004
17Nephrectomy
01/2020 - 04/2007
13Stents
01/2021 - 01/2012
13Cystectomy
11/2020 - 09/2006
9Lithotripsy (Extracorporeal Shockwave Lithotripsy)
01/2021 - 01/2012
8Prostatectomy (Retropubic Prostatectomy)
10/2020 - 10/2005
6Radiotherapy
10/2020 - 06/2013
6Solid-State Lasers
06/2013 - 08/2012
5Nephroureterectomy
05/2019 - 05/2015
5Nephrotomy
05/2019 - 01/2012
5Neoadjuvant Therapy
05/2019 - 09/2006
5Percutaneous Nephrolithotomy
10/2012 - 01/2012
4Catheters
01/2021 - 07/2011
4Orchiectomy (Orchidectomy)
03/2019 - 01/2016
3Lymph Node Excision (Lymph Node Dissection)
08/2021 - 10/2006
3Renal Dialysis (Hemodialysis)
05/2019 - 07/2011
3Operative Time
05/2017 - 08/2012
2Brachytherapy
10/2020 - 06/2016
2Chemoradiotherapy
09/2020 - 12/2011